Polyphyllin E
Polyphyllin E
CAS: 76296-73-6
Molecular Formula: C51H82O20
Polyphyllin E - Names and Identifiers
Polyphyllin E - Physico-chemical Properties
| Molecular Formula | C51H82O20 |
| Molar Mass | 1015.2 |
| Density | 1.43 |
| Appearance | Powder |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
Polyphyllin E - Reference
| Reference Show more | 1. [IF=2.233] Yinglei Liu et al."Polyphyllin E inhibits proliferation, migration and invasion of ovarian cancer cells by down-regulating the AKT/NF-κB pathway."Biological & Pharmaceutical Bulletin. 2022 Feb 19 |
Polyphyllin E - Introduction
Polyphyllin E(Polyphyllin E) is a natural organic compound extracted from the roots of the polyphylla plant, belonging to the class of saponins. Its chemical formula is C51H82O20 and its molecular weight is 1037.18g/mol.
Polyphyllin E has a variety of biological activities, especially in anti-tumor and anti-virus showed good potential. It has been found to have a cytotoxic effect on a variety of cancer cells, inhibiting the proliferation and growth of these cells. In addition, Polyphyllin E also has an inhibitory effect on some viruses, especially in the anti-HIV and hepatitis B virus shows a certain activity.
The method of preparing Polyphyllin E is generally obtained by extracting from the rhizome of Polyphyllin plants. Specific extraction methods include ultrasonic-assisted extraction, water extraction, alcohol extraction and organic solvent extraction. Subsequently, by column chromatography, thin layer chromatography, gel filtration and high performance liquid chromatography and other techniques for separation and purification, and finally get a single Polyphyllin E.
Regarding its safety information, Polyphyllin E is relatively safe at a certain dose. However, excessive use may cause some side effects, such as nausea, vomiting, gastrointestinal discomfort and dizziness. At the same time, due to its toxic effects on the heart and liver, for safety reasons, appropriate dosage and use guidelines should be followed when using Polyphyllin E. In addition, pregnant women, lactating women and patients with heart or liver disease should avoid the use of the compound. Before using Polyphyllin E, it is best to consult the advice of a doctor or pharmacist.
Polyphyllin E has a variety of biological activities, especially in anti-tumor and anti-virus showed good potential. It has been found to have a cytotoxic effect on a variety of cancer cells, inhibiting the proliferation and growth of these cells. In addition, Polyphyllin E also has an inhibitory effect on some viruses, especially in the anti-HIV and hepatitis B virus shows a certain activity.
The method of preparing Polyphyllin E is generally obtained by extracting from the rhizome of Polyphyllin plants. Specific extraction methods include ultrasonic-assisted extraction, water extraction, alcohol extraction and organic solvent extraction. Subsequently, by column chromatography, thin layer chromatography, gel filtration and high performance liquid chromatography and other techniques for separation and purification, and finally get a single Polyphyllin E.
Regarding its safety information, Polyphyllin E is relatively safe at a certain dose. However, excessive use may cause some side effects, such as nausea, vomiting, gastrointestinal discomfort and dizziness. At the same time, due to its toxic effects on the heart and liver, for safety reasons, appropriate dosage and use guidelines should be followed when using Polyphyllin E. In addition, pregnant women, lactating women and patients with heart or liver disease should avoid the use of the compound. Before using Polyphyllin E, it is best to consult the advice of a doctor or pharmacist.
Last Update：2024-04-10 22:29:15
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CAS: 76296-73-6
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CAS: 76296-73-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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